Robshaw lifted the 144-year-old trophy at Murrayfield last year as England's new brigade launched the Stuart Lancaster era with a battling 13-6 victory.
If England were taking a step into the unknown on that occasion, on Saturday they will run out in front of an expectant crowd at Twickenham.
Scotland have not won at the home of English rugby for 30 years and their most recent match ended in a humbling defeat to Tonga, a result which cost Andy Robinson his job as head coach.
England, meanwhile, return to the scene of their record triumph over New Zealand steeled for a Scottish backlash and determined to bring Twickenham to its feet again.
"It is always a massive occasion. We spoke in the week about the honour of playing in the oldest international rugby fixture in history," Robshaw said.
"You don't get many opportunities to play special games like that.
"Both sides will be fully aware of what the game means and the history and rivalry between the two countries.
"It is a completely new challenge to last year. We were a new coaching team, new players and no-one really knew what to expect from us.
"This is a new challenge. People expect different things from us and as players it is about rising to that challenge.
"I have a very talented and great group around me who enjoy going out there and playing rugby. I think that showed in the autumn.
"There were some tough times as well. Every time we go out there we are going out to work hard for the nation, for the fans who have come to watch us and hopefully perform well for them."
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