Stuart Hogg is to make his first Test start at full-back, with his Glasgow Warriors team-mates John Barclay and Graeme Morrison recalled at blindside flanker and inside centre, respectively.
Mike Blair has been called up at scrum-half, with two positional switches - Sean Lamont moving from inside to outside centre and Rory Lamont from full-back to the right wing.
Two of the changes were enforced, with Barclay replacing Alasdair Strokosch, who has been ruled out of the tournament with a fractured hand, and wing Max Evans unavailable for selection due to an ankle injury.
Scotland team: S Hogg (Glasgow Warriors); R Lamont (Glasgow Warriors), S Lamont (Scarlets), G Morrison (Glasgow Warriors), L Jones (Edinburgh); G Laidlaw (Edinburgh), M Blair (Edinburgh); A Jacobsen (Edinburgh), R Ford (capt, Edinburgh), G Cross (Edinburgh), R Gray (Glasgow Warriors), J Hamilton (Gloucester), J Barclay (Glasgow Warriors), R Rennie (Edinburgh), D Denton (Edinburgh).
Replacements: S Lawson (Gloucester), E Kalman (Glasgow Warriors), A Kellock (Glasgow Warriors), R Vernon (Sale Sharks), C Cusiter (Glasgow Warriors), D Weir (Glasgow Warriors), N De Luca (Edinburgh).
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.