England's interim coach Stuart Lancaster was forced into making the late change after Strettle failed a fitness test on a sternum injury.
Sharples' only previous Test appearance came as a second-half replacement in England's World Cup warm-up win against Wales last August.
Lancaster said: "Charlie has trained with us throughout the tournament so he has spent a lot of time with the other guys.
"He almost made the World Cup squad and this is a great opportunity for him.
"It's unfortunate for David but he has been fitness-tested by the medics this morning and is not 100 per cent so it is a straight swap and Charlie is ready to go."
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.