Flanker Stephen Ferris accused the English of being "bad losers" earlier in the week, while full-back Rob Kearney stated Ireland's recent dominance of the fixture is because they are the superior team.
But Best refused to pour more fuel on the fire ahead of a showdown that should determine who finishes Six Nations runners-up.
"We know that in past we've had some very tough games against England and we expect nothing different tomorrow," the Ulster hooker said.
"At this level nobody particularly likes losing because we're very competitive players. You only get to the top of sport by being competitive.
"I've always found that if it's been a tough, hard game, you have that respect for each other.
"Historically England have always been there or thereabouts as Grand Slam champions.
"When I was growing up England dominated this tournament. Once you're lucky enough to play for Ireland you want to beat the best and that's what England have been."
Ireland have won seven of their last eight Six Nations meetings with England, including three of the last four at Twickenham, but Best insisted that record is irrelevant on Saturday.
"Unfortunately our record won't have any impact - those games are in the past. It's all about what happens at 5pm tomorrow evening," the 29-year-old said.
"As far as we're concerned we're playing the reigning Six Nations champions in their own back yard.
"They've won three of their four outings so we know they're a very tough team.
"We're looking forward to it but we're under no illusions over the size of the challenge. The past is the past."
England still have a mathematical chance of retaining their title and have surpassed all expectations under the guidance of interim head coach Stuart Lancaster.
Best, who will eclipse Keith Wood's milestone of 58 Test appearances to become Ireland's most capped hooker, has been impressed by their progress.
"England have been very efficient so far. They negotiated two banana skins against Scotland and Italy very well," he said.
"They upped the level of performance against Wales and then upped it again last weekend.
"They look like a team that's hungry to win for each other and that rings alarm bells for any team playing them.
"When you have that hunger to succeed, it goes a long way."
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.