McCaw is struggling with a minor calf injury and Muliaina has a tight hamstring, so the duo join Dan Carter in being rested for the clash against the minnows.
In McCaw's absence, hooker Keven Mealamu will lead the side while Adam Thomson shifts to openside and Victor Vito comes off the bench to start at No.8. Lock Anthony Boric comes in to the squad on the bench
With Israel Dagg (right abdominal strain) also unavailable Isaia Toeava will now start at full-back.
All Blacks coach Graham Henry said: "It's disappointing to have the players unavailable, especially Richie and Mils who were both looking forward to playing against Japan.
"But injuries are something that we all have to deal with and it's great that we have versatility in the squad so Isaia is able to slot in at full-back."
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.