A foot injury has sidelined skipper McCaw for final pool clash - and with New Zealand having already qualified, it has been decided not to risk the flanker.
Carter's injury looks more serious, though, with the fly-half having injured his groin in training.
Victor Vito and Colin Salde come into the side as a result, with Mils Muliaina, Sonny Bill Williams, Jimmy Cowan, Kieran Read, Andrew Hore and Ali Williams all handed starts.
Canada have made two changes for their line-up for the clash - with the Canucks looking to secure the third-placed finish they need to for automatic qualification to the next World Cup.
With full-back James Pritchard having been injured during the thrilling 23-23 draw with Japan, Conor Trainor is promoted to the starting XV.
Trainor will come in on the wing, with Matt Evans dropping back into the No.15 jersey.
Coach Kieran Crowley, a former All Black, has made two further changes on the bench. Nanyak Dala comes into replace Evans, while Andrew Tiedemann comes in for Jeremy Kyne.
New Zealand: 15 Mils Muliaina, 14 Israel Dagg, 13 Conrad Smith, 12 Sonny Bill Williams, 11 Zac Guildford, 10 Colin Slade, 9 Jimmy Cowan, 8 Kieran Read, 7 Victor Vito, 6 Jerome Kaino, 5 Ali Williams, 4 Samuel Whitelock, 3 Owen Franks, 2 Andrew Hore (c), 1 Tony Woodcock.Replacements: 16 Keven Mealamu, 17 Ben Franks, 18 Brad Thorn, 19 Anthony Boric, 20 Piri Weepu, 21 TBC, 22 Isaia Toeava.
Canada: 15 Matt Evans, 14 Conor Trainor, 13 DTH Van Der Merwe, 12 Ryan Smith, 11 Phil Mackenzie, 10 Ander Monro, 9 Ed Fairhurst, 8 Aaron Carpenter, 7 Chauncey O'Toole, 6 Adam Kleeberger, 5 Jamie Cudmore, 4 Jebb Sinclair, 3 Jason Marshall, 2 Pat Riordan (captain), 1 Hubert Buydens. Replacements: 16 Ryan Hamilton, 17 Scott Franklin, 18 Andrew Tiedemann, 19 Tyler Hotson, 20 Nanyak Dala, 21 Sean White, 22 Nathan Hirayama.
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.