Andy Farrell is sure England's inexperienced side can thrive on the hostility, history and "chaos" that lies in wait for them against Scotland.
Duncan Weir racked up 20 points as Scotland A claimed a 35-0 win over England Saxons at Galashiels on Friday.
Chris Robshaw says England's young guns will be undaunted by the history and hostility of Murrayfield in Saturday's Calcutta Cup clash (5pm).
Scotland scrum-half Chris Cusiter believes a winning start to the Six Nations is imperative against England, saying: "We simply have to do it".
Andy Robinson believes Scotland are ready to realise their potential and start the Six Nations with a bang in Saturday's opener with England.
Dan Parks is determined Scotland can deliver against England on Saturday and spark a successful Six Nations campaign.
Old hurts and new hopes will all be in the air when Scotland and England start their Six Nations campaign with the latest edition of international rugby union's oldest match in Edinburgh on Saturday.
Alasdair Strokosch is known as a master of the dark arts and will play a key role if Scotland are to win the Six Nations opener with England.
Sean Lamont is wary of Scotland shedding their underdog tag ahead of Saturday's Six Nations opener with a new-look England.
Ross Ford is desperate for Scotland to shed the tag of "unlucky losers" - and that quest starts with a revenge mission against England.
Allan Jacobsen is determined to make amends for the frustrations and hurt of the World Cup campaign at the upcoming Six Nations tournament.
Scotland new boys Dave Denton and Lee Jones are hoping to make immediate impacts after being called up for the Calcutta Cup clash with England.
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