Coach Heyneke Meyer has responded to calls to include the 20-year-old fly-half at the expense of his regular 10, the out-of-form Morne Steyn.
Goosen's selection is one of three changes, with locks Andries Bekker and Eben Etzebeth also recalled.
There could be a fourth alteration too, with Francois Steyn battling an ankle injury and Jaco Taute standing by.
South Africa: Zane Kirchner; Bryan Habana, Jean de Villiers, Francois Steyn, Francois Hougaard; Johan Goosen, Ruan Pienaar; Tendai Mtawarira, Adriaan Strauss, Jannie du Plessis, Eben Etzebeth, Andries Bekker, Francois Louw, Willem Alberts, Duane Vermeulen.
Replacements: Tiaan Liebenberg, Coenie Oosthuizen, Flip van der Merwe, Marcell Coetzee, Elton Jantjies, Jaco Taute, Pat Lambie.
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
$29.99
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.