Six Nations side Italy will visit the United States for a June 23 match against the Eagles to be played at Houston.
The Eagles will host the Italians in the first international event on the new home pitch of Major League Soccer's Houston Dynamo, a 22,000-seat stadium still under construction but set to open in May.
The Americans will be guided by new coach Mike Tolkin, who replaced former Irish national team coach Eddie O'Sullivan, who resigned last November.
In their most recent meeting, Italy downed the US men 27-10 in a first-round match at last year's World Cup in New Zealand.
"In New Zealand we struggled to match the power of the Italian forwards," Tolkin said.
"They played a forwards-oriented game, slowed our ball down, and made us struggle in the set piece on both sides of the ball.
"The intensity will be there on our part, but we'll need to match that power in Houston. These are the types of games that the Eagles need to play to improve, and eventually, we need to start winning them as well."
The Eagles will also visit Canada on June 9 at Kingston and play host to Georgia on June 16.
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The Barbarians are one of the top invitational rugby sides with a long history and classic rugby jersey.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Lions get ready for their matches with this green training jersey. It's what the players wear. Get in the Gear!
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The Lions are ready to get their Australia tour underway. They arrive in Perth on Monday.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.