Time is running out for the Falcons, who host Saracens next Friday and then visit Wasps a fortnight later, in their quest for top-flight survival.
"We have had Gloucester watched and we know what to expect from them," Newcastle rugby director Gary Gold said.
"It is important that we go down there with a positive mindset and take the energy that we had against Sale two weeks ago into the game.
"We are also realistic and we are very disappointed with our away performances, certainly since I have been here. It is something that I would dearly like to put right."
Mike Tindall and Eliota Fuimaono-Sapolu return to Gloucester's midfield as the Cherry and Whites look to maintain their quest for Heineken Cup qualification through a top-six finish. One change in the forwards sees lock Alex Brown replace Tom Savage.
Gold makes four changes for the trip to Kingsholm. Greg Goosen replaces injured full-back Jeremy Manning, while Ryan Shortland gains a start on the wing and there are also roles for lock James Hudson and number eight Adam Balding.
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
$29.99
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.