England's interim head coach Stuart Lancaster has taken the strong disciplinary action because it was Care's second alcohol-related incident in three weeks.
The Harlequins scrum-half was fined for being drunk and disorderly after being arrested in the early hours of December 10, following his club's Heineken Cup defeat to Toulouse.
Although Care was also fined a "substantial" amount by Harlequins, England took no further disciplinary action on that occasion.
But after the latest incident over the festive season Lancaster has now decided to come down strongly on the 25-year-old, who missed the World Cup with a foot injury but was certain of a place in England's Six Nations plans.
The squad will be announced on January 11.
But Lancaster has met with Care, told him his behaviour is not what is expected of an England player and that he will not be included in either the senior or Saxons squads.
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.