Hooker David Paice joins the Kiwi in the front row with Matt Garvey starting at lock and Alex Gray getting the nod at number eight. Behind the scrum Jonathan Spratt comes into midfield while Adrian Jarvis starts ahead of Steven Shingler, currently engulfed in a row over his international eligibility, at fly-half.
Sale boss Steve Diamond has tweaked his pack as prop Tony Buckley and flanker Onosa'i Auva'a replace Henry Thomas and David Seymour respectively. James Gaskell moves into the second row as Scotland international Richie Vernon starts in the back row.
Diamond said: "We're going down to one of the most difficult away venues. London Irish are a side whose results can be hard to predict, but they'll be fired up after their reverse at Bath last Sunday," he said.
"We'll be travelling with a largely similar team to that which played at Leicester, and with the same mindset."
Exiles counterpart Toby Booth said: "Consistency comes from continuity in selection. It would be nice to be able to select the same team two weeks in a row. Having said that the boys coming in have done well in the earlier part of the season and get the chance to put on the shirt in a very important time of the season for us."
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.