The duo are available again after returning from World Cup duty, while United States international Hayden Smith is also selected in the second row.
In the backline, Rodd Penney gets a start on the wing while Joe Maddock switches to full-back.
Owen Farrell starts the game at fly-half with Charlie Hodgson and Alex Goode both named amongst the replacements.
They are joined on the bench by England prop Matt Stevens and back rower Matt Hankin, who will make his full Saracens debut should he be called into action.
Meanwhile, Exeter, who were the only side to defeat Sarries on home soil in the Aviva Premiership last season, have made three changes - all in their back division - for the trip to Watford.
Coach Rob Baxter has opted to give Australian Pat Phibbs and Mylse Dorrian their first starts for the Chiefs, the duo replacing Kevin Barrett and Jack Nowell respectively.
The other alteration from the line-up that started last week's victory over the Ospreys sees Josh Tatupu come in for Bryan Rennie in the centres.
On the bench, Samoan international Junior Poluleuligaga comes into the match-day squad for the first time this season following his exertions at the Rugby World Cup.
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.