In what is set to be an 80,000 sell-out, Turner-Hall returns from injury to replace Tom Casson in the one change to the back-line which toppled mighty Toulouse in the Heineken Cup last week, one of the greatest of all Harlequins' victories.
Up front Joe Marler and Chris Brooker return to the front row in place of Mark Lambert and Joe Gray, and Will Skinner, suspended following his red card in France, is replaced by Maurie Fa'asavalu.
Saracens give Ireland veteran Peter Stringer his first start since joining from Munster with Ben Spencer dropping to the bench, the only change to their back-line from last week's win over the Ospreys.
But Mark McCall is forced into changes in his pack, with Jacques Burger ruled out for eight weeks after undergoing knee surgery this week.
Andy Saull comes in to replace him, and in the second row George Kruis starts in place of Mouritz Botha. In the front row Carlos Nieto comes in with Matt Stevens dropping to the bench.
Harlequins: Brown, Stegmann, Hopper, Turner-Hall, Monye, Evans, Care, Marler, Brooker, Johnston, Vallejos, Robson, Fa'asavalu, Robshaw, Easter
Replacements: Gray, Lambert, Fairbrother, Matthews, Wallace, Bolt, Clegg, Williams
Saracens: Goode, Strettle, Farrell, Barritt, Short, Hodgson, Stringer, Gill, Brits, Nieto, Borthwick, Kruis, Brown, Saull, Joubert
Replacements: George, Smit, Stevens, M Botha, Wray, Spencer, Powell, Wyle
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