Matt Stevens is named on the bench after being released by England and scrum-half Ben Spencer also returns from duty with England U20s.
"We've enjoyed another excellent week of preparation and are really looking forward to the game against Leicester," said director of rugby Mark McCall.
"Leicester come to us on the back of a defeat to Exeter Chiefs but before that match, they had shown the type of form that has made them one of the most consistent sides in the Premiership.
"They have a squad full of internationals with a lot of experience, so we know that all aspects of our game must be at the very highest levels on Sunday."
Meanwhile, Samoa international prop Logoviii Mulipola is given his first Aviva Premiership start for Leicester in the trip to Watford.
The 24-year-old tighthead has his opportunity in the absence of Dan Cole, Martin Castrogiovanni and Julian White, and joins internationals Marcos Ayerza and George Chuter in the Tigers front-row.
James Grindal and Matt Smith come into the backline in changes following defeat at Exeter Chiefs last Saturday.
Sam Harrison (ankle) and Alesana Tuilagi (knee) are ruled out after picking up injuries at Exeter, but Manu Tuilagi, Toby Flood and Thomas Waldrom return from the England training camp to take starting roles.
Craig Newby, who captained Tigers in the Aviva Premiership Final against Saracens in May, is named among the replacements as he continues his return from injury,
Scotland Under-20s scrum-half Scott Steele joins England Under-20s fly-half George Ford in the matchday squad.
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
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Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
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The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.