Warburton, whose London-born father Jeremy lived in Birmingham before moving to Cardiff as a boy, does not view the English as public enemy number one.
"I have a number of relatives in the north, and my grandmother speaks with a Yorkshire accent," said the Cardiff Blues flanker.
"I never thought about making myself available for England, but I did support them in the 2003 World Cup in Australia.
"I am not like a lot of other Welshmen who have an anti-English attitude, even if my thoughts this week are about beating them on Saturday."
Warburton was at high school playing soccer in the same team as current Tottenham and Wales star Gareth Bale when England conquered the rugby world.
But he is rapidly making a name for himself with an oval ball, having already won 15 caps and now ready to skipper Wales instead of an injured Matthew Rees, a task he filled effortlessly against the Barbarians in June.
Warburton is just 22, but even though Wales possess such star names as Shane Williams, Jamie Roberts, James Hook and Mike Phillips, current form suggests he could easily be the first name written on coach Warren Gatland's team-sheet.
"I feel more relaxed about being captain than I did the first time - it will be a bit easier," he added.
"It will be a step up from the Barbarians, and the fact it is England will give it extra spice.
"Everyone mentions what happened at Twickenham four years ago (Wales were humbled 62-5 in a World Cup warm-up Test), and we are keen to rectify that.
"But we are about looking forwards, not backwards, concentrating on the positive. This is effectively our first game of the season, and there will be some sore bodies on Sunday.
"We have got into game-mode this week after focusing all summer on training, and we are confident we can put in a good performance at Twickenham.
"Confidence is key going into a World Cup, and we want to get a big scalp to put us in a good position going into our first game in New Zealand against South Africa.
"We know we are going to be rusty and we will not be perfect. There will be mistakes, but the performance will be second to the result."
Wales' last two World Cup preparation fixtures against England in 2003 and 2007 saw them concede a total of 105 points and score just 14.
There is no pre-match repeat of four years ago, though, when Gatland's predecessor Gareth Jenkins selected a horribly-weakened team for Twickenham.
Saturday's line-up features only two survivors from that dismal day - Ospreys forwards Huw Bennett and Alun-Wyn Jones - and it contains five British and Irish Lions Test players in Jones, Shane Williams, Jamie Roberts, Stephen Jones and Mike Phillips.
And Wales should also have no question marks hovering over their fitness, having emerged from two punishing camps at the Olympic training village in Spala, Poland.
"We got a lot out of them," said Warburton. "Sometimes we had three sessions a day, and the quality was high.
"We had our fitness results earlier this week, and there were 21 personal bests, with players smashing their old records. It shows that our preparations have worked."
And whatever happens between now and whenever Wales conclude their World Cup campaign in New Zealand, regular trips to a cryotherapy chamber and 6am training sessions will not be easily forgotten.
The human-sized fridges, which can plummet to a temperature of minus 160 degrees centigrade, help aid and speed up players' recovery. Warburton christened them "evil saunas."
"The room was full of dry ice, as you might expect, and this is what makes it reminiscent of a sauna, albeit a particularly painful and evil one," he said.
"There is a small window in the door that you can look out of, but, apart from that, the conditions are pretty claustrophobic and my first experience of the chamber was a nervous one.
"Obviously, as soon as you go in the cold hits you, and you have to keep moving around just to be able to stand it.
"But then your skin temperature begins to drop and you can see the ice form on the hairs of the boys' chests and you start to feel pain searing round your body.
"Some people take music in on headphones and, if you can listen to a whole song, then you know you've pretty much done it and it's time to get out.
"I would be lying if I didn't say it was a pretty savage experience, but the other side of the coin was that it definitely worked and allowed us to train in a way that would be impossible under normal conditions."
England: D Armitage (London Irish); M Banahan (Bath Rugby), M Tuilagi (Leicester Tigers), R Flutey (London Wasps), M Cueto (Sale Sharks); J Wilkinson (Toulon), D Care (Harlequins); A Corbisiero (London Irish), D Hartley (Northampton Saints), M Stevens (Saracens), S Shaw (Unattached), T Palmer (Stade Francais), T Croft (Leicester Tigers), L Moody (Bath Rugby, capt), J Haskell (Ricoh Black Rams).
Replacements: L Mears (Bath Rugby), D Wilson (Bath Rugby), M Botha (Saracens), T Wood (Northampton Saints), R Wigglesworth (Saracens), C Hodgson (Saracens), C Sharples (Gloucester Rugby).
Wales: R Priestland (Scarlets); G North (Scarlets), J Davies (Scarlets), J Roberts (Cardiff Blues), S Williams (Ospreys); S Jones (Scarlets), M Phillips (Bayonne); P James (Ospreys), H Bennett (Ospreys), C Mitchell (Exeter), B Davies (Cardiff Blues), A-W Jones (Ospreys), D Lydiate (Newport Gwent Dragons), S Warburton (Cardiff Blues, capt), T Faletau (Newport Gwent Dragons).
Replacements: L Burns (Newport Gwent Dragons), R Bevington (Ospreys), L Charteris (Newport Gwent Dragons), R Jones (Ospreys), T Knoyle (Scarlets), S Williams (Scarlets), M Stoddart (Scarlets).
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