Victory for Steve Diamond's men would strengthen their quarter-final hopes on the tournament's opening weekend.
"We have had a good week preparing for this game," Diamond said.
"Brive will be difficult, though, as they are a well-organised team, but we are determined to get something from the game.
"We have got to make sure we go into this next period of games ensuring that we iron out those little errors."
Ireland prop Tony Buckley makes his first start for the Sharks, while Mark Easter replaces Richie Vernon in the back row. Mark Cueto drops out, with Tom Brady replacing him on the wing.
Saturday's other Amlin Challenge Cup fixtures see Newport Gwent Dragons visiting Italian side Cavalieri Prato, Bayonne travelling to Rovigo and Agen tackling Spanish tournament newcomers La Vila.
Sale Sharks team v Brive: Miller; Brady, Leota, Tuitupou (capt), Addison; MacLeod, Cliff; Dickinson, Taylor, Buckley; McKenzie, Gaskell; Easter, Seymour, Powell.
Replacements: M Jones, Imiolek, Thomas, Myall, Vernon, Willis, Burrell, Higgins.
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.