The pair had scans on calf and knee complaints respectively, with the results confirming that both would have to bypass the game.
Pocock had been scheduled to return to playing duties after last having appeared during the opening match of this year's Rugby Championship against the All Blacks. He has been sidelined since with a medial ligament injury.
Douglas, who has had a dramatic week after his mother was hospitalised in London after becoming ill on her flight over from Australia last Friday, featured in last weekend's Test match against France at Paris.
Wallabies medical staff will re-assess the injuries to both Pocock and Douglas next week once the side has arrived in Italy ahead of the third match of their European tour against the Azzurri in Florence.
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The Barbarians are one of the top invitational rugby sides with a long history and classic rugby jersey.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Lions get ready for their matches with this green training jersey. It's what the players wear. Get in the Gear!
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The Lions are ready to get their Australia tour underway. They arrive in Perth on Monday.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.