The coach has brought in Clermont Auvergne hooker Benjamin Kayser for his debut at the expense of Dimitri Szarzewski, while Morgan Parra comes in for Maxime Machenaud at scrum-half and Thomas Domingo replaces Yannick Forestier at loosehead prop.
Castres full-back Brice Dulin retains his place in the starting line-up for the contest at Stade de France despite picking up a thigh injury in last weekend's 39-22 win over Argentina.
Victory for France this weekend will ensure they remain in fourth place in the world rankings and therefore be among the top seeds for the 2015 World Cup when the draw is made on December 3.
France team:
Brice Dulin (Castres); Wesley Fofana (Clermont Auvergne), Florian Fritz (Toulouse), Maxime Mermoz (Toulon), Vincent Clerc (Toulouse); Frederic Michalak (Toulon), Morgan Parra (Clermont Auvergne); Fulgence Ouedraogo (Montpellier), Louis Picamoles (Toulouse), Yannick Nyanga (Toulouse); Yoann Maestri (Toulouse), Pascal Pape (capt, Stade Francais); Nicolas Mas (Perpignan), Benjamin Kayser (Clermont Auvergne), Thomas Domingo (Clermont Auvergne)
Replacements: Dimitri Szarzewski (Racing Metro), Yannick Forestier (Castres), Vincent Debaty (Clermont Auvergne), Jocelino Suta (Toulon), Damien Chouly (Clermont Auvergne), Maxime Machenaud (Racing Metro), Francois Trinh-Duc (Montpellier), Yoann Huget (Toulouse).
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
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Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
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The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
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The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.