Substitute scrum-half Eoin Reddan has been ruled out for three months after suffering a broken leg during Ireland's Six Nations draw with France.
Reddan fell awkwardly beneath a tackle in the final minute of a compelling 13-13 draw at the Aviva Stadium and was given oxygen before being carried off.
Ireland's injury-depleted ranks were swelled even further by a number of other casualties, with lock Donnacha Ryan damaging his shoulder and centre Luke Marshall sustaining concussion.
Both are doubts to face Italy next Saturday but head coach Declan Kidney, already missing a host of players, refused to complain about his side's misfortune.
"We took a conscious decision that we wouldn't complain about things. Other people are worse off than we are, plus it's such an insult to the lads coming on and having a huge go," Kidney said.
"We're frustrated, but there are lads coming in who have no experience at this level under their belts and are doing such a good job for us.
"On any given day Paul O'Connell, Tommy Bowe, Stephen Ferris and Jonathan Sexton would be in the running for a Lions spot.
"I've never experienced an injury run like this, but you work your way through and I spoke to (captain) Jamie Heaslip about it and we agreed not to complain."
For the third successive match of the championship Ireland let slip victory, having led 13-3 at the interval but Kidney insisted his players' spirit through adversity was to be saluted.
"The players have taken everything that's been thrown at them and just got on with it," he added.
"So to put our foot forward like that and be creating in the way we are doing actually adds to the frustration.
"The players are down, but that's the measure of how much they push themselves and why I stand by them so much.
"In another time the team would be so much stronger for what's happening at the moment."
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The Barbarians are one of the top invitational rugby sides with a long history and classic rugby jersey.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Lions get ready for their matches with this green training jersey. It's what the players wear. Get in the Gear!
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The Lions are ready to get their Australia tour underway. They arrive in Perth on Monday.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.