The injury-hit RBS 6 Nations champions have suffered six consecutive defeats, and have registered losses against Argentina, Samoa and New Zealand so far this autumn.
Saturday's game against the Wallabies gives Gatland's side one last chance to avoid dropping out of the world's top eight ahead of Monday's 2015 World Cup draw.
It also gives them another shot at ending their miserable run against the top three teams in the game.
In 20 games against Australia, New Zealand or South Africa since Gatland took charge in 2007, Wales have claimed a solitary success.
But Gatland knows his side will need to get a greater share of the 50/50 refereeing decisions than they have done so far this autumn.
Gatland, who revealed Wales have received two apologies from referees for incorrect decisions during the autumn window, said: "You just say to referees 'give us a chance' with some of the 50/50 calls.
"I said to Craig Joubert (who refereed Wales against New Zealand) that I look at games - and I am not questioning the integrity of referees here - thinking 'that's a bit of a rough call against us' and I also think 'where are the tough calls against them?'.
"It's the old Manchester United scenario where they get 70-odd per cent of the 50/50 calls.
"But you have to create your own luck and that's up to us putting ourselves in the minds of referees in terms of them not refereeing us so much or allowing the opposition to get away with a bit."
But Gatland made it clear he believes his side have received some rough justice in recent weeks, including from Wayne Barnes, who will take charge of the Test against the Wallabies.
"On Saturday in the first minute there could easily have been a red card (for Andrew Hore's challenge on Bradley Davies)," he said.
"At the first breakdown Richie McCaw has come in from the side and not been penalised, Aaron Jarvis has gone to clean him out and got injured.
"The referee against Samoa apologised to Rob Howley for a neck throw on Ken Owens and said it should have been a yellow card.
"Wayne Barnes was on the line and put his flag out for a penalty, but it should have been a minimum of a yellow card and those are the 50/50 calls you are looking to hopefully go your way.
"Referees don't go into games favouring one team or another, but sometimes you have to change that perception.
"We have to work harder for them maybe not being prepared to potentially referee an upset. It's that balance."
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