Tournament debutants Montpellier welcome European Cup champions Leinster to the south of France on Saturday.
Fabien Galthie's side made it through to the quarterfinal stage of the Amlin Challenge Cup last season, but their form has seen them win just two of their opening nine games in the French Top 14.
A host of Internationals have return to Stade Yves du Manoir but with former Champions Bath their next opponents following Leinster it will be a tough few first weeks in the European Cup.
Leinster's pedigree makes impressive reading - two European Cup titles in the past three seasons.
After lifting the crown in a thrilling final in Cardiff back in May confidence will be high for the Irish province heading to France for their opening encounter.
Leinster have won all their games on the road in France during the past two seasons and will be hoping their fortunes continue as they begin the 2011/12 season.
A major blow for the Champions is the loss of inspirational centre Brian O'Driscoll who has been ruled out with a neck / shoulder injury until May.
Montpellier: 15 Lucas Amorosino, 14 Timoci Nagusa, 13 Geoffrey Doumayrou, 12 Santiago Fernandez, 11 Yoan Audrin, 10 Francois Trinh-Duc, 9 Benoit Paillaugue, 8 Masi Matadigo, 7 Mamuka Gorgodze, 6 Fulgence Ouedraogo, 5 Thibaut Privat, 4 Mickael Demarco, 3 Maximiliano Bustos, 2 Agustin Creevy, 1 Na'ama Leleimalefaga.
Replacements: 16 Rassie Jansen Van Vuuren, 17 Mikheil Nariashvili, 18 George Jgenti, 19 Drickus Hancke, 20 Rémy Martin, 21 Julien Tomas, 22 Paul Bosch, 23 Martin Bustos Moyano.
Leinster: 15 Rob Kearney, 14 Isa Nacewa, 13 Fergus McFadden, 12 Gordon D'Arcy, 11 Luke Fitzgerald, 10 Johnny Sexton, 9 Isaac Boss, 8 Jamie Heaslip, 7 Sean O'Brien, 6 Kevin McLaughlin, 5 Damian Browne, 4 Leo Cullen, 3 Mike Ross, 2 Richardt Strauss, 1 Heinke Van Der Merwe.
Replacements: 16 Sean Cronin, 17 Jack McGrath, 18 Nathan White, 19 Devin Toner, 20 Shane Jennings, 21 Eoin Reddan, 22 Ian Madigan, 23 Eoin O'Malley.
Date: Saturday, November 12
Venue: Stade Yves Du Manoir, Montpellier
Kick-off: 14.30 (13.30 GMT)
Referee: Dave Pearson (England)
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The Barbarians are one of the top invitational rugby sides with a long history and classic rugby jersey.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Lions get ready for their matches with this green training jersey. It's what the players wear. Get in the Gear!
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The Lions are ready to get their Australia tour underway. They arrive in Perth on Monday.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.