Jacques Burger and Ben Spencer both come into the starting line-up. Schalk Brits' three-week suspension sees Smit make a full debut while Burger returns after missing last week through injury.
Scrum-half Spencer comes into the starting XV with Neil de Kock ruled out with an arm injury.
On the replacements bench, Mouritz Botha, Jamie George and Luke Baldwin all come into the matchday 23.
The reigning English champions ran in five tries in their impressive 42-17 win over Treviso last weekend and we be looking for a second away win to will put them in control of Pool Five.
But two-time Heineken Cup finalists Biarritz have an impressive record at the Stade Aguilera losing only four of their 38 Heineken Cup games there.
The Basques will be looking to bounce back from defeat to the Ospreys although they did manage to salvaging a losing bonus point in Swansea.
The return of the World Cup players means BO will field a much stronger team than the outfit that has left the club dead last in the Top 14 but they will be missing playmaker scrum-half Dimitri Yachvili.
Biarritz Olympique: 15 Dane Haylett-Petty, 14 Taku Ngwenya, 13 Benoît Baby, 12 Damien Traille, 11 Iain Balshaw, 10 Marcelo Bosch, 9 Luix Roussarie, 8 Raphael Lakafia, 7 Imanol Harinordoquy, 6 Benoit Guyot, 5 Erik Lund, 4 Jerome Thion, 3 Sylvain Marconnet, 2 Benoit August, 1 Fabien Barcella.
Replacements: 16 Arnaud Heguy, 17 Yvan Watremez, 18 Francisco Gomez Kodela, 19 Pelu Taele, 20 Florian Faure, 21 Yann Lesgourgues, 22 Julien Peyrelongue, 23 Ilikena Bolakoro.
Saracens: 15 Chris Wyles, 14 David Strettle, 13 Owen Farrell, 12 Brad Barritt, 11 James Short, 10 Charlie Hodgson, 9 Ben Spencer, 8 Ernst Joubert, 7 Jacques Burger, 6 Kelly Brown, 5 Hayden Smith, 4 Steve Borthwick, 3 Matt Stevens, 2 John Smit, 1 Rhys Gill.
Replacements: 16 Jamie George, 17 Deon Carstens, 18 Carlos Nieto, 19 Mouritz Botha, 20 Andy Saull, 21 Luke Baldwin, 22 Adam Powell, 23 Alex Goode.
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.