Harlequins will put their unbeaten record this season on the line when they host the four-times Heineken Cup champions, Toulouse, at the Twickenham Stoop on Friday night.
The English Premiership side are still the only side who have a flawless winning record this season, having won all 12 games in their domestic and European competitions.
But something will have to give when the French giants visit the English capital, with both teams unbeaten in Pool Six and looking to secure qualification for the knock-out stages of the tournament.
Toulouse, the moist successful side in the Heineken Cup and the aristocrats of French rugby, have recorded two impressive, if unspectacular, wins over Gloucester and Connacht to put themselves in top of their Pool.
The Quins, who lifted the Amlin Challenge Cup in Cardiff last season, have been the talk of English and European rugby with their perfect start of the season and have made no secret of their lofty ambitions in this seasons Heineken Cup.
Harlequins: 15 Mike Brown, 14 Seb Stegmann, 13 Matt Hopper, 12 Benjamin Urdapilleta, 11 Sam Smith, 10 Nick Evans, 9 Danny Care, 8 Nick Easter, 7 Chris Robshaw (c), 6 Maurie Fa'asavalu, 5 George Robson, 4 Tomas Vallejos, 3 James Johnston, 2 Chris Brooker, 1 Joe Marler
Replacements: 16 Joe Gray, 17 Mark Lambert, 18 Kyle Sinckler, 19 Charlie Matthews, 20 Luke Wallace, 21 Richard Bolt, 22 Rory Clegg, 23 Ugo Monye.
Toulouse: 15 Maxime Medard, 14 Vincent Clerc, 13 Florian Fritz, 12 Yannick Jauzion, 11 Timoci Matanavou, 10 Luke McAlister, 9 Luke Burgess, 8 Louis Picamoles, 7 Thierry Dusautoir, 6 Yannick Nyanga, 5 Yoann Maestri, 4 Grégory Lamboley, 3 Census Johnston, 2 Gary Botha, 1 Jean-Baptiste Poux.
Replacements: 16 William Servat, 17 Yohan Montes, 18 Johnson Falefa, 19 Romain Millo-Chluski, 20 Jean-Marc Doussain, 21 Yves Donguy, 22 Yann David , 23 Shaun Sowerby.
Date: Friday, 9 December
Venue: The Stoop
Kick-off: 20:00 GMT
Referee: George Clancy (Ireland)
Assistant referees: Leo Colgan (Ireland), Ken Beggs (Ireland)
TMO: Peter Ferguson (Ireland)
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