Cardiff Blues will be looking to record their six straight victory over Edinburgh when the two sides meet in their first of back-to-back Pool Two clashes at the Cardiff City Stadium.
The sides from the Welsh and Scottish capital are both unbeaten so far this campaign but the Blues, who have won the last five games between the sides, will be favourites on home soil.
Edinburgh, who top Pool Two after narrow one-point wins over London Irish and Racing Metro 92, will be hoping to end their disappointing run of defeats to the fellow Pro12 side on Friday night.
The Scots will be hoping to carry on their march to reach a first knock-out place since 2004 and only their second quarterfinals berth in the 15 seasons of the Heineken Cup.
The Blues will be hoping to extend their current run of five wins, in all competitions, on the trot against Edinburgh and to reach a quarterfinals place for the first time in two seasons.
Cardiff Blues: 15 Leigh Halfpenny, 14 Alex Cuthbert, 13 Casey Laulala, 12 Jamie Roberts, 11 Chris Czekaj, 10 Dan Parks, 9 Lloyd Williams, 8 Xavier Rush, 7 Sam Warburton, 6 Michael Paterson, 5 Paul Tito, 4 Bradley Davies, 3 Tau Filise, 2 T Rhys Thomas, 1 Gethin Jenkins.
Replacements: 16 Ryan Tyrrell, 17 John Yapp, 18 Scott Andrews, 19 Maama Molitika, 20 Josh Navidi, 21 Richie Rees, 22 Ceri Sweeney, 23 Gavin Evans.
Edinburgh: 15 Chris Paterson, 14 Lee Jones, 13 Nick De Luca, 12 James King, 11 Tim Visser, 10 Harry Leonard, 9 Greig Laidlaw, 8 Stuart McInally, 7 Roddy Grant, 6 David Denton, 5 Esteban Lozada, 4 Sean Cox, 3 Geoff Cross, 2 Ross Ford, 1 Allan Jacobsen.
Replacements: 16 Steve Lawrie, 17 Kyle Traynor, 18 Jack Gilding, 19 Steve Turnbull, 20 Ross Rennie, 21 Mike Blair, 22 John Houston, 23 Tom Brown.
Date: Friday, December 9
Venue: Cardiff City Stadium
Kick-off: 20:00 GMT
Referee: Wayne Barne
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