Cardiff Blues will be determined to keep their unbeaten record in Pool 2 and to cement their position as leaders as they continue the hunt for a quarterfinal place.
The Welsh region have won all of their three Pool games so far and will be looking to do the double over Edinburgh in the top of the table clash at Murrayfield on Friday.
The Scotish side, who lie in second in the Pool, have won six of their last eight home games in the Heineken Cup and will be looking to build on their recent home victory over French side, Racing Metro.
But the Cardiff Blues, who have beaten London Irish, Racing Metro and Edinburgh in their Pool, are looking for their first Heineken Cup quarter-finals place in three seasons.
Edinburgh: 15 Chris Paterson, 14 Lee Jones, 13 Nick De Luca, 12 James King, 11 Tim Visser, 10 Greig Laidlaw (captain), 9 Mike Blair, 8 Netani Talei, 7 Roddy Grant, 6 David Denton, 5 Sean Cox, 4 Grant Gilchrist, 3 Geoff Cross, 2 Ross Ford, 1 Allan Jacobsen.
Replacements: 16 Steven Lawrie, 17 Kyle Traynor, 18 Jack Gilding, 19 Esteban Lozada, 20 Ross Rennie, 21 Phil Godman, 22 Matt Scott, 23 Tom Brown.
Cardiff: 15 Leigh Halfpenny, 14 Gavin Evans, 13 Casey Laulala, 12 Jamie Roberts, 11 Chris Czekaj, 10 Dan Parks, 9 Lloyd Williams, 8 Xavier Rush, 7 Sam Warburton, 6 Michael Paterson, 5 Paul Tito, 4 Bradley Davies, 3 Tau Filise, 2 T Rhys Thomas, 1 Gethin Jenkins.
Replacements: 16 Ryan Tyrrell, 17 John Yapp, 18 Scott Andrews, 19 Josh Navidi, 20 Maama Molitika, 21 Richie Rees, 22 Ceri Sweeney, 23 Dafydd Hewitt.
Date: Friday, December 16
Kick-off: 20.00 (20:00 GMT)
Referee: Pascal Gauzere
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