Harlequins will be looking to build on their victory over Toulouse in France when they host Gloucester at the Twickenham Stoop in their penultimate game of the pool stages.

The English Premiership outfit are one-point behind Pool Six leaders Toulouse and need to ensure they emerge with a home win to keep their chances of a Heineken Cup quarterfinal place alive.

Both sides are still very much in contention for a place in the knock-out stages of the tournament and four-times champions, Toulouse, are still in the sights of both English clubs.

Gloucester, who are only three points behind Quins in the pool table, will harbour ambitions of their own to challenge for a place in the last eight of European rugby's premier competition.

The Cherry and Whites managed a narrow and hard-fought 23-19 victory over Connacht in the last game of the pool and will be happy to come away with the same from the English capital.

Harlequins: 15 Mike Brown, 14 Tom Williams, 13 Matt Hopper, 12 Jordan Turner-Hall, 11 Ugo Monye, 10 Nick Evans, 9 Danny Care, 8 Nick Easter, 7 Chris Robshaw (captain), 6 Maurie Fa'asavalu, 5 Charlie Matthews, 4 Olly Kohn, 3 James Johnston, 2 Joe Gray, 1 Mark Lambert
Replacements: 16 Chris Brooker, 17 Joe Marler, 18 Tim Fairbrother, 19 Tomas Vallejos, 20 Luke Wallace, 21 Richard Bolt, 22 Rory Clegg, 23 Tom Casson.

Gloucester: 15 Jonny May, 14 Charlie Sharples, 13 Mike Tindall, 12 Eliota Fuimaono-Sapolu, 11 James Simpson-Daniel, 10 Freddie Burns, 9 Rory Lawson, 8 Luke Narraway (captain) 7 Akapusi Qera, 6 Alasdair Strokosch, 5 Alex Brown, 4 Jim Hamilton, 3 Dario Chistolini, 2 Scott Lawson, 1 Nick Wood.
Replacements: 16 Darren Dawidiuk, 17 Dan Murphy, 18 Rupert Harden, 19 Will James, 20 Matt Cox, 21 Dave Lewis, 22 Ryan Mills, 23 Henry Trinder.

Date: Saturday, January 14
Venue: The Twickenham Stoop
Kick-off: 18:00 GMT
Referee: Pascal Gauzere (France)