Captain Greig Laidlaw (shoulder) has been ruled out and is replaced by Gregor Hunter as one of five changes from the side which lost 45-0 to Saracens last weekend.
Scotland tighthead Geoff Cross has been named to start, with Fiji captain Netani Talei brought in at number eight.
Talei's selection sees Stuart McInally accommodated at openside flanker at the expense of Ross Rennie, in a big back row, which also features David Denton.
Greig Tonks and Ben Atiga have recovered from hand and hip injuries respectively to be named at full-back and centre.
Tonks has started every available match since joining from Northampton in the summer.
Munster lost their opening match 22-17 to Racing Metro and Bradley knows a win in Limerick is essential if Edinburgh are to emulate their run to last year's semi-finals.
"There's no doubt that this is a massive game for us, but it's also a big chance for us to get our European Cup campaign moving and challenge the teams in this group," Bradley said.
"Thomond Park is a fortress, steeped in the Heineken Cup history. The fans and the players will be fired up for this, so we'll need to front up to the physical aspects of the game from the outset.
"If we match them physically, and are patient and accurate in possession, then we have a chance to impose our game plan and not be dictated to by the Munster players and a Thomond Park crowd that will be desperate for a home win."
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The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
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