Clermont Auvergne centre Wesley Fofana and Toulouse lock Yoann Maestri are rewarded for their outstanding club form, while Saint-Andre has also recalled several players deemed surplus to requirements by his predecessor Marc Lievremont.
Among them are the Toulouse trio of Clement Poitrenaud, Lionel Beauxis and Yannick Nyanga. Fly-half Beauxis last played for Les Bleus in 2009, while flanker Nyanga has not featured since the 2007 World Cup.
However, there is no place for centre Mathieu Bastareaud or scrum-half Julien Dupuy.
Former Sale, Gloucester and Toulon coach Saint-Andre has retained 22 of the squad that reached the World Cup final in October and the exceptional Toulouse flanker Thierry Dusautoir, the IRB World Player of the Year, will retain the captaincy.
The squad will be put through their paces during a three-day training camp later this month ahead of their tournament opener against Italy in Paris on Saturday, February 4.
Provisional 30-man squad for the RBS 6 Nations.
Forwards: Fabien Barcella (Biarritz), Vincent Debaty (Clermont), Luc Ducalcon (Castres), Nicolas Mas (Perpignan), Jean-Baptiste Poux (Toulouse), William Servat (Toulouse), Dimitri Szarzewski (Stade Francais), Yoann Maestri (Toulouse), Romain Millo-Chluski (Toulouse), Pascal Pape (Stade Francais), Julien Pierre (Clermont), Imanol Harinordoquy (Biarritz), Thierry Dusautoir (Toulouse, capt), Fulgence Ouedraogo (Montpellier), Yannick Nyanga (Toulouse), Louis Picamoles (Toulouse), Julien Bonnaire (Clermont)
Backs: Morgan Parra (Clermont), Dimitri Yachvili (Biarritz), Lionel Beauxis (Toulouse), Francois Trinh-Duc (Montpellier), Yann David (Toulouse), Wesley Fofana (Clermont), Maxime Mermoz (Perpignan), Aurelien Rougerie (Clermont), Vincent Clerc (Toulouse), Julien Malzieu (Clermont), Alexis Palisson (Toulon), Maxime Medard (Toulouse), Clement Poitrenaud (Toulouse).
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