England on Thursday named three new caps in the starting team to face Scotland in Saturday's Six Nations match at Murrayfield.
Saracens midfielder Brad Barritt and Owen Farrell will form a new centre pairing at international level, while Northampton Saints' Phil Dowson makes his debut at No.8.
The match 22 sees five more uncapped players on the replacements' bench - Rob Webber (London Wasps), Geoff Parling (Leicester Tigers), Ben Morgan (Scarlets), Lee Dickson (Northampton Saints) and Jordan Turner-Hall (Harlequins).
Head coach Stuart Lancaster said: "We have been impressed with how the whole group has come together in the last 10 days and we have done a lot of work on and off the field.
"Now is the time to turn all that into a performance against Scotland that we can all be proud of. It is a massive challenge – Murrayfield, the first game of the Six Nations – but one we are relishing."
England: 15 Ben Foden, 14 Chris Ashton, 13 Brad Barritt, 12 Owen Farrell, 11 David Strettle, 10 Charlie Hodgson, 9 Ben Youngs, 8 Phil Dowson, 7 Chris Robshaw, 6 Tom Croft, 5 Tom Palmer, 4 Mouritz Botha, 3 Dan Cole, 2 Dylan Hartley, 1 Alex Corbisiero.
Replacements: 16 Rob Webber, 17 Matt Stevens, 18 Geoff Parling, 19 Ben Morgan, 20 Lee Dickson, 21 Jordan Turner-Hall, 22 Mike Brown.
Date: Saturday, February 4
Venue: Murrayfield, Edinburgh
Kick-off: 17.00 (17.00 GMT)
Referee: George Clancy (Ireland)
Assistant referees: Romain Poite (France), Leighton Hodges (Wales)
TMO: Tony Redmond (Ireland)
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